Abstract

Dear colleagues, Asalamu Alykum

Welcome to the group of dermatologists in Libya, which hosts specialists and dermatologists and those who are involved in the training program for specialization, through which subjects related to the specialization are posted in the form of different formulas and scenarios, for example clinical patient photos or theoretical topics for discussion or the introduction of

topics of medical literature for enrichment Discussion, sharing and

exchange of experiences among fellows in the CME course

In view of the privacy of the group in terms of which medical cases are reviewed with pictures of patients, it is necessary to join those with the

real name of the doctor and do not accept the aliases and only admission to

doctors and their names the truth and we hope from the colleagues

appreciate this point. In order to protect us from individual ownership, it is

not permissible to present pictures of patients' cases except by the doctor

concerned. It should be noted that there is no room in this group for

advertising propaganda and promotional all types and keep them as a

scientific group and even the names of drugs must be mentioned scientific

names. I also hope that all members will participate actively and enrich the

discussion so that the benefit will prevail. May Allah guide us all to what

is good and God is behind the intention.

Thyroid function is impaired by diabetes,

resulting into thyroid disorders, accompanied by

the alteration of thyroid-stimulating hormone

(TSH) and thyroxine (T4) levels. The aim of this

study was to investigate the role of vitamin D

supplementation on TSH and total T4 levels in

serum of Libyan patients suffering from type 2

diabetes mellitus

(T2DM) with thyroid

disorders. A total of 180 subjects were recruited

and distributed into two groups: 80 participants

in control group (43 females and 37 males), with

an age range of 26-72 years, and 100

participants in T2DM patient group (54 females

and 46 males), with an age range of 26-63 years.

Each T2DM patient received a monthly

intramuscular injection of 200000 ng/ml vitamin

D for three months. Glucose, vitamin D, total T4

and TSH levels were determined in serum

samples of healthy subjects and of T2DM

patients (pre- and post-administration of vitamin

D). After the T2DM group received vitamin D

supplementation, the mean of vitamin D level

increased in the T2DM, while the mean of

glucose level decreased. Most importantly, the

mean of total T4 level for patients increased

significantly (p ˂ 0.05) from 1.34 to 8.23 g/dL,

both of which were lower than the control group

mean 10.99 g/dL. In contrast, the mean of TSH

level for patients decreased significantly (p ˂

0.05) from 11.77 to 2.71 mU/L, and both values

were greater than the control group mean 2.01

mU/L. ANOVA results showed that age, gender,

and body mass index had no significant

individual interactions (p > 0.05) with vitamin D

supplementation on total T4 and TSH levels.

Vitamin D supplementation had a beneficial role

on total T4 and TSH levels in serum of Libyan

T2DM patients with thyroid disorders.

Keywords: T2DM, thyroid disorder, total T4,

TSH, vitamin D supplementation, ANOVA, t

test.

Abstract

Background: Warts are a common skin condition that affects people all over the world. This ailment affects 2–20% of students in primary school. A well-known keratolytic agent, potassium hydroxide (KOH), has many dermatological uses. Vitamin D is important in the proliferation and differentiation of keratinocytes.

Objective: The aim of the current work was to compare the efficacy and safety of intralesional vitamin D3 injections and 5% KOH cream separately and in combination with each other in the treatment of warts.

Patients and Methods: This study was carried out at the private outpatient Al- Ahlam Center of Dermatology and Cosmetology in Gharyan, Libya from 1^st of Sep to last of Dec 2021. 45 patients with warts were included in the study. They were classified into 3 groups according to method of treatment into Vitamin D3 group, 5% KOH cream group, and combination group.

Results: The mean age of patients was 27.04 ± 11.7 years. 31 patients completed the study. Complete response was seen in 12 patients with vitamin D injection after period of 4 months, 9 patients with 5% KOH cream after period 2-3 months, and 10 patients with combination both treatment after a period of 1 month.

Conclusions: It could be concluded that intralesional vitamin D with 5% KOH cream is safe, effective, and inexpensive treatment option for recalcitrant palmoplantar and periungual warts.

 KeywordsVitamin D3; Palmoplanter; Periungual; KOH; Warts

Background/ Objectives: Vitamin D deficiency has been found to be associated with glycated hemoglobin (HbA1c) levels amongst

patients with diabetes mellitus type 2 (DM2). However, the beneficial effect of vitamin D supplementation on HbA1c levels in DM2

patients has been investigated and its role remains controversial. The purpose of this study was to examine the role of vitamin D

supplementation on HbA1c levels amongst Libyan patients suffering from DM2.

Methods and design: Ninety-seven DM2 patients of both genders (M = 51) (F = 46), with an age range of 26-59 years, were recruited

from the Al-Wafi Medical Laboratory in Tripoli, Libya. All patients were informed about the nature of the study and oral consent was

obtained from all patients. Weight and height were measured, and dietary and lifestyle information was obtained. Blood samples were

collected and HbA1c and vitamin D levels were measured pre-and post-the administration of vitamin D supplementation for three

months. The participants were divided into three groups according to HbA1c level, and then into four groups, based on their vitamin

D serum levels. The relationship between vitamin D and HbA1c was investigated.

Results: Vitamin D levels have increased after the administration of vitamin D supplementation amongst DM2 patients. We noticed

that the level of HbA1c also decreased from 6.97% at the baseline to 5.65% after supplementation of vitamin D. The results showed

that the difference in HbA1c levels was significant after administration of vitamin D as a supplement (P-value = 0.000). The level of

vitamin D increased from 8.34±2.59 to 39.95±2.85 ng/ml after the administration of the supplements. In mixed ANOVA analysis, the

present study confirmed that the relationship between HbA1c and the factors measured appear to be weak and these findings indicate

that HbA1c was not influenced by all these factors studied.

Conclusions: The results of this study have shown that vitamin D supplementation significantly reduced the level of HbA1c amongst

patients suffering from DM2. These results may be beneficial for the overall health and blood glucose control of those patients.

Abstract

Background:Acne vulgaris is the most common skin condition affecting the pilosebaceoussystemin adolescents and young age and characterized bydifferentskinlesionsand might result in permanent scars. Chemical peeling is an effective option in the management of active acne. The mechanism of action lies in causing desquamation by targeting the corneosomes and keratinocytes, enhancing breakdown and decreasing cohesiveness. It also increases epidermal activity of enzymes, leading to epidermolysis and exfoliation and induces improvement of skin texture , pore size and reduces sebum production. Proper and successful treatment of acne involves choosing the right medication. Objectives:This study aims to evaluate the clinical efficacy and safety of using topical 25% Salicylic acid alone, in comparison with a combination of systemic Azithromycin and topical 25% salicylic acid, Zinc sulphate, and Benzoyl peroxide gel, in treatment of mild to moderate acne lesions. Subjects and methods:This study is a prospective, randomized clinical trial included a hundred patients diagnosed with mild-to-moderate facial acne vulgaris and randomly divided into two equal groups Group A, treated by25% Salicylic Acid peeling in combination with systemic Azithromycin in addition to Zinc sulphate and topical Benzoyl peroxide gel. Group B, treated by 25% salicylic peeling only.All patients received at least 6 peeling sessions performed 2 weeks apart in 12-weeks duration. Results:Number of peeling sessions was significantly lower in group A than group Bp= 0.03. Improvement rate (92%) 46 cases in group A vs. (20%) 10 cases in group B.Improvement score after 6th session was 4.71 in group A vs 2.67in group Bp<0.001.Also, there was a highly significant improvement after each session in group A as 15 cases (30%) needed only 4 sessions for complete improvement. group B showed only significant improvement after 2nd,3rd, and 4th sessions, while there was no improvement in score after 5th and 6thsessions.There were no statistically significant differences regarding risk factors of acne such as; psychological distress, family history, dairy product consumption, fast food, cosmetics, regular exercise and special diet habits p>0.05. Disease duration were matched in both groups as mean duration in group A was 26.8 versus 27.5 months in group B. Back & shoulder lesion were found in 34 cases in group A while they present in 31 cases in group B. There were no differences regarding lesions characteristics between both studied groups except for pustules that were predominant in group A in 34/50 cases (68%) whereas, they found in 24/50 cases (48%) in group Bp=0.04. Conclusion:Topical 25 % of salicylic acid is more efficient to treat mild to moderate acne vulgaris andincombinationwith systemic Azithromycin in addition to Zinc sulphate and topical Benzoyl peroxide gel is significant than alone and both protocols equal in safety and tolerability. Keywords:Acne Vulgaris, Salicylic Acid,Chemical Peeling, Benzoyl Peroxide.

Comparison Between Secondary School Pupils' English Achievement in General Certificate of Secondary Education And Their Health Sciences College English Admission Test Achievement

The Impact of Professional Schemata on the Reading Comprehension of Libyan University Students Studying ESP in the College of Health Sciences-Gharyan

This study reviewed using peer correction as a teaching technique in dictation exercise and explored the attitude of second year university students studying health sciences in the Colleague of Health Sciences in Gharyan towards peer correction. More than seventy students participated in this study. The study participants exposed to lecturer's feedback and colleague's feedback and their attitudes towards both techniques were measured by using a questionnaire. The results revealed that the majority of the questionnaire respondents preferred their dictation exercise to be corrected by their lecturer, while a small number of the respondents favoured their colleagues' feedback. The participants gave many reasons behind their preferences. These reasons were discussed in relation to the advantages and limitations of peer correction presented in the literature review. It seems that preparation, both psychologically and linguistically, is needed before applying peer correction to get the hopeful benefit of this teaching technique.

Key words: peer correction, lecturer' feedback, teaching technique

The bacterial strain (Bacillus subtilis) was isolated from soil sample using different composed culture for alkaline protease production in Submerged Fermentationby. The eight different submereged media were prepared to study of enzyme activity. Then the effect of pH, carbon sources nitrogen sources, Nacl concentration and metal ions on protease production were studied. The results indicated to: MD8 produced highest amount of alkaline protease (62.5 U /ml), The extracted crude enzyme was precipitated using varied precentages of ammonium sulphate was studied. The effect of pH,carbon,nitrogen sources sodium chloride concentration and metal ions was studied here and results tom maximum enzyme activity was as pH11 to MD4(17.97U/ml),glucose showed maximum yield in MD2(49.21U/ml) ammonium chloride affected maximum (132.81U/ml) to MD6 and the maximum activity was seen in case of MD5 with 11%NaCl(46.09U/ml) and lastly the metal ions effect was Mncl2(85.94U/ml))